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早先一篇文章说CRISPR基因技术不够安全,会引起很多无关的突变:
In the initial Nature Methods paper, scientists from Stanford and University of Iowa working to cure blindness in mice found that while CRISPR did successfully edit the gene for blindness, it also caused mutations in more than a thousand unrelated genes.
文章发表后引起很多领域内科学家的反弹,认为数据不严谨。
最新一篇文章对这一结果进行了重新解释,认为CRISPR基因编辑技术是足够安全的:
This week, a pre-print of a second paper published by scientists at Intellia that reanalyzed the original paper’s data and found far fewer off-target edits also appeared online.
见:
Gene Editing Controversy Reminds Us Just How Much Money Influences Science
另见:
CRISPR gene editing technique is probably safe, study confirms
DNA mutations blamed on CRISPR more likely because lab mice Colt Clan like inbreeding
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CRISPR Gene Editing Controversy: Does It Really Cause Unexpected Mutations?
CRISPR Gene Editing Controversy: Does It …
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