10月5日至12日，2026年的诺贝尔全部奖项均已尘埃落定。这些奖项不仅是对杰出科学家及其卓越发现的崇高认可，更是当代科学技术与文化艺术领域探索的璀璨展现，为科学界乃至全社会的进步提供了宝贵的启示与指引。诺贝尔奖得主们在攀登科学高峰的征途中，留下了哪些影响深远的学术篇章？

我们特别汇集了2026年诺贝尔奖得主在Wiley旗下期刊发表的部分学术论文，与读者共同回顾科学巨匠的智慧结晶。

诺贝尔生理学或医学奖

2025年诺贝尔生理学或医学奖颁给了Karl Deisseroth、Peter Hegemann和Georg Nagel，以表彰他们在光控离子通道及光遗传学相关成果的发现。

Karl Deisseroth在Wiley发表的文章包括：

• A Guide to Creating and Testing New INTRSECT Constructs

Lief E. Fenno, Joanna Mattis, Charu Ramakrishnan, Karl Deisseroth

Current Protocols in Neuroscience Volume 80, Issue 1 pp. 4.39.1-4.39.24

https://doi.org/10.1002/cpns.30

Peter Hegemann在Wiley旗下期刊发表数十篇文章：

• Evolution of the Channelrhodopsin Photocycle Model

Katja Stehfest Dr., Peter Hegemann Dr.

ChemPhysChem Volume 11, Issue 6 pp. 1120-1126

https://doi.org/10.1002/cphc.200900980

• Early Formation of the Ion-Conducting Pore in Channelrhodopsin-2

Jens Kuhne, Kirstin Eisenhauer, Dr. Eglof Ritter, Prof. Dr. Peter Hegemann, Prof. Dr. Klaus Gerwert, Prof. Franz Bartl

Angewandte Chemie International Edition Volume 54, Issue 16 pp. 4953-4957

https://doi.org/10.1002/anie.201410180

• Glu 87 of Channelrhodopsin-1 Causes pH-dependent Color Tuning and Fast Photocurrent Inactivation

Satoshi P. Tsunoda, Peter Hegemann

Photochemistry and Photobiology Volume 85, Issue 2 pp. 564-569

https://doi.org/10.1111/j.1751-1097.2008.00519.x

• The chromophore structure of the long-lived intermediate of the C128T channelrhodopsin-2 variant

Sara Bruun, Hendrik Naumann, Uwe Kuhlmann, Claudia Schulz, Katja Stehfest, Peter Hegemann, Peter Hildebrandt

FEBS Letters Volume 585, Issue 24 pp. 3998-4001

https://doi.org/10.1016/j.febslet.2011.11.007

• Photophobic responses and phototaxis in Chlamydomonas are triggered by a single rhodopsin photoreceptor

Petra Kröger, Peter Hegemann

FEBS Letters Volume 341, Issue 1 pp. 5-9

https://doi.org/10.1016/0014-5793(94)80229-7

• Tailoring Organic LEDs for Bidirectional Optogenetic Control via Dual-Color Switching

Giuseppe Ciccone, Ilenia Meloni, Rodrigo G. Fernandez Lahore, Johannes Vierock, Sebastian Reineke, Hans Kleemann, Peter Hegemann, Karl Leo, Caroline Murawski

Advanced Functional Materials  Volume 32, Issue 12 2110590

https://doi.org/10.1002/adfm.202110590

Georg Nagel在Wiley发表的文章包括：

• Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

Xiao Duan, Chong Zhang, Stanislav Ott, Zhiyi Zhang, Christiane Ruse, Sven Dannhäuser, Robert Jacobi, Nadine Ehmann, Divya Sachidanandan, Georg Nagel, Manfred Heckmann, Robert J. Kittel, Alexander Gottschalk, Adam Claridge-Chang, Shiqiang Gao

Advanced Science Volume 13, Issue 6 e09180

https://doi.org/10.1002/advs.202509180

• PACα– an optogenetic tool for in vivo manipulation of cellular cAMP levels, neurotransmitter release, and behavior in Caenorhabditis elegans

Simone Weissenberger, Christian Schultheis, Jana Fiona Liewald, Karen Erbguth, Georg Nagel, Alexander Gottschalk

Journal of Neurochemistry Volume 116, Issue 4 pp. 616-625

https://doi.org/10.1111/j.1471-4159.2010.07148.x

• Optogenetic tools for manipulation of cyclic nucleotides functionally coupled to cyclic nucleotide-gated channels

Thilo Henß, Jatin Nagpal, Shiqiang Gao, Ulrike Scheib, Alessia Pieragnolo, Alexander Hirschhäuser, Franziska Schneider-Warme, Peter Hegemann, Georg Nagel, Alexander Gottschalk

British Journal of Pharmacology Volume 179, Issue 11 pp. 2519-2537

https://doi.org/10.1111/bph.15445

• Functional expression of bacteriorhodopsin in oocytes allows direct measurement of voltage dependence of light induced H+ pumping

Georg Nagel, Bettina Möckel, Georg Büldt, Ernst Bamberg

FEBS Letters Volume 377, Issue 2 pp. 263-266

https://doi.org/10.1016/0014-5793(95)01356-3

• Cardiac Na+ -Ca2+ Exchange System in Giant Membrane Patches

DONALD W. HILGEMANN, ANTHONY COLLINS, DAVID P. CASH, GEORG A. NAGEL

Annals of the New York Academy of Sciences Volume 639, Issue 1 pp. 126-139

https://doi.org/10.1111/j.1749-6632.1991.tb17296.x

• Cardiac Chloride Channels: Incremental Regulation by Phosphorylation/Dephosphorylationa

DAVID C. GADSBY, TZYH-CHANG HWANG, MINORU HORIE, GEORG NAGEL, ANGUS C. NAIRN

Annals of the New York Academy of Sciences Volume 707, Issue 1 pp. 259-274

https://doi.org/10.1111/j.1749-6632.1993.tb38057.x

• Apparent affinity of CFTR for ATP is increased by continuous kinase activity

Tanjef Szellas, Georg Nagel

FEBS Letters Volume 535, Issue 1-3 pp. 141-146

https://doi.org/10.1016/S0014-5793(02)03892-9

诺贝尔物理学奖

2026年的诺贝尔物理学奖授予了比利时裔美国科学家Francis Halzen，以表彰他对冰立方中微子观测台的决定性贡献，以及对天体物理来源高能中微子的发现。

Francis Halzen在Wiley发表的文章包括：

• High-Energy Neutrinos from the Cosmos

Francis Halzen

Annalen der Physik Volume 533, Issue 11 2100309

https://doi.org/10.1002/andp.202100309

• The Era of Kilometer-Scale Neutrino Detectors

Francis Halzen, Uli Katz

Advances in High Energy Physics Volume 2013, Issue 1 680584

https://doi.org/10.1155/2013/680584

• Cosmic Accelerators

Francis Halzen

Annals of the New York Academy of Sciences Volume 490, Issue 1 pp. 237-256

https://doi.org/10.1111/j.1749-6632.1987.tb40378.x

诺贝尔化学奖

2026年诺贝尔化学奖授予法国科学家Henri B. Kagan与日本科学家Kenso Soai，表彰他们在不对称有机合成中发现非线性效应和自催化现象。

Henri B. Kagan在Wiley发表60余篇文章，包括：

• Nonlinear Effects in Asymmetric Synthesis and Stereoselective Reactions: Ten Years of Investigation

Christian Girard, Henri B. Kagan

Angewandte Chemie International Edition Volume 37, Issue 21 pp. 2922-2959

https://doi.org/10.1002/(SICI)1521-3773(19981116)37:21<2922::AID-ANIE2922>3.0.CO;2-1

• Nonlinear Effects in Asymmetric Catalysis

Tummanapalli Satyanarayana Dr., Susan Abraham Dr., Henri B. Kagan Prof.

Angewandte Chemie International Edition Volume 48, Issue 3 pp. 456-494

https://doi.org/10.1002/anie.200705241

• Asymmetric Amplification by Kinetic Resolution Using A Racemic Reagent: Example in Amine Acetylation

Tummanapalli Satyanarayana Dr., Henri B. Kagan Prof.

Chemistry–A European Journal Volume 12, Issue 22 pp. 5785-5789

https://doi.org/10.1002/chem.200600026

• Metallocene Sulfoxides as Precursors of Metallocenes with Planar Chirality

Benoit Ferber, Henri B. Kagan

Advanced Synthesis & Catalysis Volume 349, Issue 4-5 pp. 493-507

https://doi.org/10.1002/adsc.200600639

• One-pot multi-substrate screening in asymmetric catalysis

Xiang Gao, Henri B. Kagan

Chirality Volume 10, Issue 1-2 pp. 120-124

https://doi.org/10.1002/chir.19

• Stoichiometric Kinetic Resolution Reactions

Mahagundappa R. Maddani, Jean-Claude Fiaud, Henri B. Kagan

Separation of Enantiomers: Synthetic Methods  Chapter 2

https://doi.org/10.1002/9783527650880.ch2

Kenso Soai在Wiley旗下期刊发表近百篇文章，包括

• Amplification of Chirality from Extremely Low to Greater than 99.5 % ee by Asymmetric Autocatalysis

Itaru Sato Dr., Hiroki Urabe, Saori Ishiguro, Takanori Shibata Dr., Kenso Soai Prof. Dr.

Angewandte Chemie International Edition Volume 42, Issue 3 pp. 315-317

https://doi.org/10.1002/anie.200390105

• Practically Perfect Asymmetric Autocatalysis with (2-Alkynyl-5-pyrimidyl)alkanols

Takanori Shibata, Shigeru Yonekubo, Kenso Soai

Angewandte Chemie International Edition Volume 38, Issue 5 pp. 659-661

https://doi.org/10.1002/(SICI)1521-3773(19990301)38:5<659::AID-ANIE659>3.0.CO;2-P

• Eine nahezu ideale asymmetrische Autokatalyse mit (2-Alkinyl-5-pyrimidyl)alkanolen

Takanori Shibata, Shigeru Yonekubo, Kenso Soai

Angewandte Chemie Volume 111, Issue 5 pp. 746-748

https://doi.org/10.1002/(SICI)1521-3757(19990301)111:5<746::AID-ANGE746>3.0.CO;2-3

• Asymmetric Self-Replication of Chiral 1,2-Amino Alcohols by Highly Enantioselective Autoinductive Reduction

Dr. Takanori Shibata, Tomohide Takahashi, Takashi Konishi, Prof. Dr. Kenso Soai

Angewandte Chemie International Edition in English Volume 36, Issue 22 pp. 2458-2460

https://doi.org/10.1002/anie.199724581

• Discovery of asymmetric autocatalysis with amplification of chirality and its implication in chiral homogeneity of biomolecules

Kenso Soai, Tsuneomi Kawasaki

Chirality Volume 18, Issue 7 pp. 469-478

https://doi.org/10.1002/chir.20289

• Asymmetric autocatalysis and the origin of chiral homogeneity in organic compounds

Kenso Soai, Itaru Sato, Takanori Shibata

The Chemical Record Volume 1, Issue 4 pp. 321-332

https://doi.org/10.1002/tcr.1017

• Asymmetric autocatalysis and its application to chiral discrimination

Kenso Soai, Itaru Sato

Chirality Volume 14, Issue 7 pp. 548-554

https://doi.org/10.1002/chir.10081

• The Origins of Homochirality Examined by Using Asymmetric Autocatalysis

Kenso Soai, Tsuneomi Kawasaki, Arimasa Matsumoto

The Chemical Record Volume 14, Issue 1 pp. 70-83

https://doi.org/10.1002/tcr.201300028

• Crystal Structure of the Isopropylzinc Alkoxide of Pyrimidyl Alkanol: Mechanistic Insights for Asymmetric Autocatalysis with Amplification of Enantiomeric Excess

Dr. Arimasa Matsumoto, Takaaki Abe, Atsushi Hara, Takayuki Tobita, Taisuke Sasagawa, Prof. Dr. Tsuneomi Kawasaki, Prof. Dr. Kenso Soai

Angewandte Chemie Volume 127, Issue 50 pp. 15433-15436

https://doi.org/10.1002/ange.201508036

• Highly enantioselective asymmetric autocatalysis of 2-alkenyl- and 2-vinyl-5-pyrimidyl alkanols with significant amplification of enantiomeric excess

Itaru Sato, Tomotaka Yanagi, Kenso Soai

Chirality Volume 14, Issue 2-3 pp. 166-168

https://doi.org/10.1002/chir.10068

• Asymmetric Synthesis of an Organic Compound with High Enantiomeric Excess Induced by Inorganic Ionic Sodium Chlorate

Itaru Sato Dr., Kousuke Kadowaki, Kenso Soai Prof. Dr.

Angewandte Chemie International Edition Volume 39, Issue 8 pp. 1510-1512

https://doi.org/10.1002/(SICI)1521-3773(20000417)39:8<1510::AID-ANIE1510>3.0.CO;2-R

• Achiral Nucleobase Cytosine Acts as an Origin of Homochirality of Biomolecules in Conjunction with Asymmetric Autocatalysis

Tsuneomi Kawasaki Dr., Kenta Suzuki, Yuko Hakoda, Kenso Soai Prof. Dr.

Angewandte Chemie Volume 120, Issue 3 pp. 506-509

https://doi.org/10.1002/ange.200703634

• Asymmetric Synthesis Utilizing Circularly Polarized Light Mediated by the Photoequilibrium of Chiral Olefins in Conjunction with Asymmetric Autocatalysis

Itaru Sato Dr., Rie Sugie, Yohei Matsueda, Yuri Furumura, Kenso Soai Prof. Dr.

Angewandte Chemie Volume 116, Issue 34 pp. 4590-4592

https://doi.org/10.1002/ange.200454162

• Asymmetric Autocatalysis: Triggered by Chiral Isotopomer Arising from Oxygen Isotope Substitution

Dr. Tsuneomi Kawasaki, Yasushi Okano, Etsuharu Suzuki, Shizuka Takano, Shotaro Oji, Prof. Dr. Kenso Soai

Angewandte Chemie Volume 123, Issue 35 pp. 8281-8283

https://doi.org/10.1002/ange.201102263

1. Asymmetric Induction by Helical Hydrocarbons: [6]- and [5]Helicenes

Itaru Sato Dr., Ryutaro Yamashima, Kousuke Kadowaki, Jun Yamamoto, Takanori Shibata Dr., Kenso Soai Prof. Dr.

Angewandte Chemie International Edition Volume 40, Issue 6 pp. 1096-1098

https://doi.org/10.1002/1521-3773(20010316)40:6<1096::AID-ANIE10960>3.0.CO;2-K

诺贝尔经济学奖

2026年诺贝尔经济学奖授予斯坦福大学教授Robert E. Hall与哥伦比亚大学教授Michael Woodford，以表彰他们在宏观经济稳定政策的微观基础方面的贡献。

Robert E. Hall在Wiley发表的文章包括：

• The Anatomy of Stagnation in a Modern Economy

Robert E. Hall

Economica Volume 84, Issue 333

https://doi.org/10.1111/ecca.12210

• Controlling the Price Level

Robert E. Hall

The American Journal of Economics and Sociology Volume 64, Issue 1

https://doi.org/10.1111/j.1536-7150.2005.00352.x

Michael Woodford在Wiley发表的文章包括：

• Credit Spreads and Monetary Policy

Vasco Curdia, Michael Woodford

Journal of Money, Credit and Banking Volume 42, Issue s1 pp. 3-35

https://doi.org/10.1111/j.1538-4616.2010.00328.x

• How Important Is Money in the Conduct of Monetary Policy?

Michael Woodford

Journal of Money, Credit and Banking Volume 40, Issue 8 pp. 1561-1598

https://doi.org/10.1111/j.1538-4616.2008.00175.x

• Monetary Policy in a World Without Money

Michael Woodford

International Finance Volume 3, Issue 2 pp. 229-260

https://doi.org/10.1111/1468-2362.00050

每位诺贝尔奖得主成功的背后都是他们数十年如一日在各自专业上的精进投入。Wiley作为权威内容与科研智慧领域的全球领导者，致力于解锁智慧潜能，帮助和陪伴诺贝尔奖得主们的科研进阶之路。

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