woodcorpse的个人博客分享 http://blog.sciencenet.cn/u/woodcorpse

博文

英国JIC院士组3.8万英镑招博后-植物代谢物与微生物组-截止6月27日

已有 488 次阅读 2019-5-31 23:36 |系统分类:科研笔记

[TOC]

博士后招聘(Osbourn实验室)

链接:https://www.jic.ac.uk/vacancies/postdoctoral-researcher-osbourn-lab/

  • 截止日期:2019年6月27日
  • 工资:31250英镑至38100英镑,视资历和经验而定。
  • 合同:截止2021年3月31日为全职。

邀请一名博士后研究人员参与Anne Osbourn教授(英国约翰英纳斯中心John Innes Centre-诺威奇 https://www.jic.ac.uk/ )和白洋研究员(中国科学院遗传学与发育生物学研究所-北京)实验室之间的合作项目。
成功的候选人将在英国诺威奇约翰英纳斯中心工作,但也将访问白洋课题组在遗传发育所的实验室,以开展与微生物组分析有关的这项工作的关键方面。

该项目由中国科学院-英国约翰英纳斯中心植物和微生物科学联合研究中心(CEPAMS)资助。

项目研究内容

根据Osbourn和白洋实验室最近发表的研究成果(《科学》2019年5月10日,详见- 《专家点评Science:中英合作揭示拟南芥三萜化合物特异调控根系微生物组》),成功的候选人将研究宿主代谢产物环境对塑造根系微生物组产生的影响。具体来说,我们将:

  1. 利用现有的转录组资源,研究了拟南芥在不同非生物胁迫和生物胁迫下根系中的生物合成基因簇表达,并通过qPCR实验验证不同环境条件对基因表达的影响。不同环境胁迫对野生型拟南芥根系微生物群落的影响将通过根系微生物组测序来确定。然后研究不同环境条件下三萜途径基因突变/过度表达对根系微生物组建立和植物适应性的影响。
  2. 对纯化的拟南芥根三萜对拟南芥土壤微生物组培养的代表性菌株生长的影响进行了体外试验,并评价了不同菌株对植物生长发育的影响。
  3. 利用一套有效的、完全解析清楚的燕麦新途径突变体,研究不同三萜类(燕麦新苷avenacins)对燕麦根系微生物组建立的影响。这些实验将揭示Avenacin通路在调节燕麦根系微生物组中的作用,并将其与拟南芥的研究结果进行比较。

理想的候选人

岗位人员将独立工作,确保研究和记录的保存符合良好实践、科学诚信和当地政策和任何法律要求。

申请者要求已经获得植物生物学或微生物学相关博士学位,并具有丰富的植物和/或微生物遗传学和分子生物学经验。有植物胁迫生物学和/或微生物组分析经验者优先。良好的沟通和人际交往能力是必不可少的。

附加信息

根据资历和经验,获得的年薪将在31250至38100英镑之间。到2021年3月31日之前这是一个全职职位。

有关如何申请的更多信息和详细信息,请访问下方申请链接或联系人力资源团队,电话:01603 450462或nbi.recruptment@nbi.ac.uk,引用编号 1003704。单击此处了解有关在John Innes中心工作的更多信息 https://data.nbi.ac.uk/Recruitment/Vacancies/FurtherInformationJIC.pdf。

我们是一个机会均等的雇主,积极支持包容性和多样性。作为一个对残疾充满信心的组织,我们保证为所有符合该职位基本标准的残疾申请人提供面试机会。约翰英纳斯中心也很荣幸地获得了雅典娜天鹅金奖(Gold Award from Athena SWAN),并且是石墙多样性冠军计划(tonewall’s Diversity Champions programme)的成员。

申请截止日期为2019年6月27日

约翰英纳斯中心是一家注册慈善机构(编号223852),由生物技术和生物科学研究理事会(BBSRC)资助,是一家机会均等的雇主。

申请链接:http://jobs.jic.ac.uk/Details.asp?vacancyID=14613

Anne Osbourn简介

image

Anne Osbourn教授,英国约翰英纳斯中心(John Innes Centre,JIC)诺里奇研究园工业生物技术联盟(Norwich Research Park Industrial Biotechnology Alliance)主任,2019年4月17月入选第30界英国皇家科学院院士(Fellow of the Royal Society),研究方向为植物天然产物的生物合成(natural product biosynthesis),包括三萜生物合成通路的发现、基因组挖掘天然产物代谢通路、天然产物及类似物的药物开发等。在Scinece、PNAS、Annual Review of Genetics、Metabolic Engineering、New Phytologist等杂志发表79篇文章。

更多个人介绍详见:https://www.jic.ac.uk/people/anne-osbourn/

Postdoctoral Researcher (Osbourn Lab)

Links:https://www.jic.ac.uk/vacancies/postdoctoral-researcher-osbourn-lab/

  • Closes: 27th June 2019
  • Salary: £31,250 to £38,100 depending on qualifications and experience
  • Contract: Full time until 31 March 2021.

Applications are invited for a Postdoctoral Researcher to work on a collaborative project between the laboratories of Professor Anne Osbourn (John Innes Centre) and Dr Yang Bai (Institute of Genetics and Developmental Biology, Beijing).

The successful candidate will be based at the John Innes Centre but will also visit Dr Bai’s lab at IGDB to carry out key aspects of this work relating to microbiome analysis.

This project is funded by the John Innes Centre – Chinese Academy of Sciences Centre of Excellence in Plant and Microbial Science Alliance (CEPAMS).

The role

Building on recently published work from the Osbourn and Bai labs (‘A specialized metabolic network selectively modulates Arabidopsis root microbiota’ Science 10 May 2019:Vol. 364, Issue 6440, eaau6389), the successful candidate will investigate the impact of the environment on production of host metabolites that sculpt root microbial communities. Specifically, they will:

  1. Use available in silico transcriptome resources to investigate the expression of Arabidopsis biosynthetic gene clusters in roots in response to different abiotic and biotic stresses and verify the effects of different environmental conditions on gene expression experimentally by qPCR.  The impact of different environmental stresses on root microbial communities in wild type Arabidopsis will be established by root microbiome sequencing. The impact of mutation/overexpression of triterpene pathway genes on root microbiota establishment and plant fitness under different environmental conditions will then be investigated
  2. Carry out in vitro tests of the effects of purified Arabidopsis root triterpenes on the growth of representative bacterial strains cultured from the Arabidopsis soil microbiota and evaluate the effects of different microbial strains on plant growth and development
  3. Investigate the impact of different triterpenes (avenacins) on root microbiome establishment in oat using a suite of available thoroughly characterised avenacin pathway mutants. These experiments will reveal the role of the avenacin pathway in regulating oat root microbiota and enable comparisons to be made with findings for Arabidopsis

The ideal candidate

The post holder will work independently and ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements.

The successful applicant will have a PhD in plant biology or microbiology and extensive experience of plant and/or microbial genetics and molecular biology. Experience of plant stress biology, and/or microbiome analysis are desirable.  Excellent communication and interpersonal skills are essential.

Additional information

Salary on appointment will be within the range £31,250 to £38,100 per annum depending on qualifications and experience.  This is a full time post available until 31 March 2021.

Further information and details of how to apply can be found here or contact the Human Resources team on 01603 450462 or nbi.recruitment@nbi.ac.uk  quoting reference 1003704.  Click here to find out more about working at the John Innes Centre.

We are an equal opportunities employer, actively supporting inclusivity and diversity.  As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. The John Innes Centre is also proud to hold a Gold Award from Athena SWAN and is a member of Stonewall’s Diversity Champions programme.

The closing date for applications will be 27 June 2019

The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council and is an Equal Opportunities Employer.

APPLY FOR THIS ROLE:http://jobs.jic.ac.uk/Details.asp?vacancyID=14613

image

猜你喜欢

写在后面

为鼓励读者交流、快速解决科研困难,我们建立了“宏基因组”专业讨论群,目前己有国内外5000+ 一线科研人员加入。参与讨论,获得专业解答,欢迎分享此文至朋友圈,并扫码加主编好友带你入群,务必备注“姓名-单位-研究方向-职称/年级”。技术问题寻求帮助,首先阅读《如何优雅的提问》学习解决问题思路,仍末解决群内讨论,问题不私聊,帮助同行。
image

学习扩增子、宏基因组科研思路和分析实战,关注“宏基因组”
image

image

点击阅读原文,跳转最新文章目录阅读
https://mp.weixin.qq.com/s/5jQspEvH5_4Xmart22gjMA



http://blog.sciencenet.cn/blog-3334560-1182351.html

上一篇:你想要的宏基因组-微生物组知识全在这(1906)
下一篇:NAR:antiSMASH数据库2—次级代谢物基因簇预测

0

该博文允许注册用户评论 请点击登录 评论 (0 个评论)

数据加载中...

Archiver|手机版|科学网 ( 京ICP备14006957 )

GMT+8, 2019-7-16 14:08

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社

返回顶部