TickingClock的个人博客分享 http://blog.sciencenet.cn/u/TickingClock


Nature Communications:拟南芥干细胞分裂调控因子

已有 708 次阅读 2019-12-8 17:48 |个人分类:每日摘要|系统分类:论文交流

Stem-cell-ubiquitous genes spatiotemporally coordinate division through regulation of stem-cell-specific gene networks

First author: Natalie M. Clark; Affiliations: North Carolina State University (北卡罗来纳州立大学): Raleigh, US

Corresponding author: Rossangela Sozzani

Stem cells are responsible for generating all of the differentiated cells, tissues, and organs in a multicellular organism and, thus, play a crucial role in cell renewal, regeneration, and organization. A number of stem cell type-specific genes have a known role in stem cell maintenance, identity, and/or division. Yet, how genes expressed across different stem cell types, referred to here as stem-cell-ubiquitous genes, contribute to stem cell regulation is less understood. Here, we find that, in the Arabidopsis root, a stem-cell-ubiquitous gene, TESMIN-LIKE CXC2 (TCX2), controls stem cell division by regulating stem cell-type specific networks. Development of a mathematical model of TCX2 expression allows us to show that TCX2 orchestrates the coordinated division of different stem cell types. Our results highlight that genes expressed across different stem cell types ensure cross-communication among cells, allowing them to divide and develop harmonically together.



讯:Ross Sozzani (https://cals.ncsu.edu/plant-and-microbial-biology/people/ross-sozzani/)



doi: https://doi.org/10.1038/s41467-019-13132-2

Journal: Nature Communications

Published date: December 06, 2019



上一篇:Current Biology:冬季油菜的春化作用和成花转变
下一篇:Nature Communications:玉米分蘖决定基因


该博文允许注册用户评论 请点击登录 评论 (0 个评论)


Archiver|手机版|科学网 ( 京ICP备14006957 )

GMT+8, 2020-1-29 04:57

Powered by ScienceNet.cn

Copyright © 2007- 中国科学报社