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Nature报道丹麦诺维信公司与河北科技大学NgAgo基因编辑技术合作
http://blog.sciencenet.cn/blog-71079-1029007.html
韩春雨副教授所在的河北科技大学,在其官网发布新闻,宣布河北科技大学基因编辑技术研究中心与丹麦诺维信公司,就ngago技术的应用与开发达成合作并签署协议,并称“双方对尽快合作推动该成果的产业化实现充满信心”。据介绍,诺维信公司是全球工业酶制剂和微生物制剂的主导企业,迄今已连续十多年在道琼斯可持续发展指数方面处于领导者地位。河北科技大学还表示该校“基因编辑技术研究中心积极推进以argonaute核酸酶为核心的基因编辑技术开发及其相关知识产权的转化和应用。目前的基因编辑技术专利主要由美国持有,韩春雨团队发现的基因编辑工具ngago-gdna为基因编辑技术提供了新的选择。”
8 Aug 2016
Replications, ridicule and a recluse: the controversy over NgAgo...
23 Nov 2016
Updated: NgAgo gene-editing controversy escalates in peer -...
20 Jan 2017
Enzyme firm invests in NgAgo protein at centre of gene-editing...
韩春雨论文被引量大增
http://blog.sciencenet.cn/blog-280034-1018406.html
DNA-guided genome editing using the Natronobacterium gregoryi Argonaute
NgAgo-gDNA and Cas9-sgRNA cleaved this locus with comparable efficiencies (Fig. 4e, 31.97% forNgAgo vs. 32.2% for Cas9). Next, we investigated whether NgAgo-gDNA ...
Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases.
The NgAgo-gDNA system did not require a PAM sequence, and could target GC-rich regions. Most of all, it had a low tolerance to guide-target mismatch, ...
Replications, ridicule and a recluse: the controversy over NgAgo gene-editing intensifies.
In the paper, Han’s team reports using a wide variety of genetic sequences to guide one of these proteins,NgAgo, to edit eight different genes in human cells and ...
Engineered endonucleases are a powerful tool for editing DNA. However, sequence preferences may limit their application. We engineer a structure-guided endonuclease (SGN) composed of flap endonuclease-…
科学网—NgAgo 能够超越 CRISPR吗?——老外评论拾碎 ...
NgAgo 能够超越 CRISPR吗?不止国内,有些老外也比较关注这个问题。世界上做基因组编辑方法和应用的实验室,差不多都有 ...
科学网—韩春雨 NgAgo 无 PAM 优势或被证明 - 岳东晓的博文
根据上图,使用 NgAgo , 导引 gDNA 可以连续滑动延展,看不出有任何限制。NgAgo + gDNA 的精确定位功能,我再引用文章中的数据说明一下。针对 斑马鱼的尾巴,下面 ...
2017-01-19
韩春雨科研团队的科研工作,给了科研人员更多的启示、反思,从中获取很好的经验和教训。 韩春雨 与丹麦诺维信公司合作 2017-1-19 16:58 澎湃新 ...(251)次阅读|(5)个评论
《自然》论文新进展
http://www.nature.com/nbt/journal/v34/n7/full/nbt.3547.html
https://nature.altmetric.com/details/7114638
in the 99 percentile (ranked 1,165th)of the 262,252 tracked articles of a similar age in all journals
in the 98 percentile (ranked 2nd)of the 123 tracked articles of a similar age inNature Biotechnology
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