Title: Identification and Accurate Size Characterization of Nanoparticles in Complex Media

Author: Lihong Liu, Bin He, Qian Liu*, Zhaojun Yun, Xueting Yan, Yanmin Long, Guibin Jiang*

Abstract: We have developed a new method for the identification and accurate size characterization of nanoparticles (NPs) in complex media based on capillary electrokinetic (CE) separation coupled to inductively coupled plasma mass spectrometry (ICP-MS). Through mass scanning and Gaussian fitting of electropherogram peaks, we can obtain multidimensional information on chemical compositions, size distributions, and ionic species of multiple NPs in a single run. The results are more accurate than those obtained by using conventional methods. This method provides a powerful tool for investigating polydisperse NP systems and rapid screening of NP-containing products.

Link: http://dx.doi.org/10.1002/anie.201408927 

关于复杂介质中纳米粒子鉴定与尺寸表征的一种新方法，主要基于CE与ICP-MS联用技术，被选为Angew Chem Int Ed杂志的VIP paper，在线发表后ChemViews杂志配发了评论文章“Getting the Measure of Nanoparticles”。（http://www.chemistryviews.org/details/ezine/6877531/Getting_the_Measure_of_Nanoparticles.html）

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