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国际上,开始用数据说中国人发表的文章到底做实验了吗?很悲哀的一件事情。
刚刚在线发表的一篇文章,法国和澳大利亚的科学家质询中国学者的文章......不知道多少人在看中国的笑话!
Striking similarities between publications from China
describing single gene knockdown experiments in human
cancer cell lines
Abstract Comparing 5publications from China that described knockdowns of the human TPD52L2 gene in human cancercell lines identified unexpected similarities between these publications, flawsin experimental design, and mis-matches between some described experiments andthe reported results. Following communications with journal editors, two ofthese TPD52L2 publications havebeen retracted. One retraction notice stated that while the authors claimedthat the data were original, the experiments had been out-sourced to a biotechnologycompany. Using search engine queries, automatic text-analysis, different similaritymeasures, and further visual inspection, we identified 48 examples of highly similarpapers describing single gene knockdowns in 1–2 human cancer cell lines thatwere all published by investigators from China. The incorrect use of aparticular TPD52L2 shRNA sequence as anegative or non-targeting control was identified in 30/48 (63%) of thesepublications, using a combination of Google Scholar searches and visualinspection. Overall, these results suggest that some publications describingthe effects of single gene knockdowns in human cancer cell lines may include theresults of experiments that were not performed by the authors. This has seriousimplications
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