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原文:In this study, novel nanosystems constituted by a model β-diketo acid (DKA) grafted to the surface of GNPs were designed and synthesized following the "multivalent high-affinity" binding strategy. These first nanoscale DKA prototypes showed improved inhibition of HIV-1 integrase (HIV-1 IN) catalytic activities as compared with free DKA ligands.
用CNKI翻译成中文:本研究遵循“多价高亲和力”结合策略,设计并合成了由接枝到GNPs表面的模型β-二酮酸( DKA )构成的新型纳米体系。这些第一个纳米级DKA原型与游离DKA配体相比,表现出对HIV-1整合酶( HIV-1 IN )催化活性的抑制提高。
再把中文用CNKI翻译成英文:In this study, a novel nanosystem consisting of model β-diketonic acid (DKA) grafted onto the surface of GNPs was designed and synthesized following the ' multivalent and high affinity ' binding strategy. Compared with free DKA ligands, these first nanoscale DKA prototypes exhibit enhanced inhibition of HIV-1 integrase ( HIV-1 IN ) catalytic activity.
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