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2006-2016诺贝尔生理医学奖论文所发表的杂志 精选

已有 10569 次阅读 2017-7-8 09:17 |系统分类:观点评述

有关诺贝尔奖获奖关键论文(Key publications)发表在了哪些杂志?大家众说纷纭。本博文对此进行了总结。由于数量庞大,本博文仅仅总结2006-2016年生理医学的论文。希望起到抛砖引玉作用,以便同行总结其他诺贝尔奖相关论文发表的杂志。

总数64篇之中,nature 22篇,占34%science 12篇,占19%cell 9篇,占14%CNS一共占67%。简单的统计结果是:2006-2016年生理医学诺贝尔奖的论文多数发表在最顶端杂志。

在这些论文中,多数是新发现,包括机理发现,治疗方法的发现。

如何创新?如何做到重大创新?仔细阅读这些论文,给我们的科研树立一个思路,树立一个典范。以前,生物医学方面的纯理论有一些,例如达尔文的进化论,拉马克的用进废退学说。但目前生物医学方面的纯理论是很少的,多数是实验性质的。少数是在实验基础之上,上升为理论的。2006-2016年的生物医学诺贝尔奖多数都是在实验基础上提出了理论学说的,把实验上升为理论的,也即把现象上升为规律。这一点恰恰是他们的高明之处,也是值得我们学习之处。

2006

Andrew Fireand/Craig C. Mello

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2007

Mario Capecchi

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Martin Evans

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Oliver Smithies

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2008

Harald zur Hausen

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Françoise Barré-Sinoussi

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Luc Montagnier

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2009

Elizabeth Blackburn, Carol W. Greider and Jack W.Szostak

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2010

Robert Edwards

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2011

Bruce Beutler

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Jules A. Hoffmann

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Ralph M. Steinman

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2012

John Gurdon

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4.Simonsson,S.; Gurdon, J. (2004). "DNA demethylationis necessary for the epigeneticreprogramming of somatic cell nuclei". Nature Cell Biology. 6 (10):984–990.

Shinya Yamanaka

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2.  Takahashi,K.; Tanabe, K.;Ohnuki, M.; Narita, M.; Ichisaka, T.; Tomoda, K.; Yamanaka, S.(2007)."Induction of Pluripotent Stem Cells from Adult Human FibroblastsbyDefined Factors". Cell. 131 (5):861–872.

3.   Okita,K.; Ichisaka, T.;Yamanaka, S. (2007). "Generation of germline-competentinduced pluripotentstem cells".Nature. 448 (7151):313–317.

2013

James Rothman

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Randy Schekman

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Thomas C. Südhof

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2014

John O'Keefe

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May-Britt Moser and Edvard Moser

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2.Sargolini, F., Fyhn, M.,Hafting, T., McNaughton, B.L., Witter, M.P., Moser,M.-B., and Moser, E.I.(2006). Conjunctive representation of position, directionand velocity inentorhinal cortex. Science, 312,754-758.

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2015

屠呦呦

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William C. Campbell

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2016

Yoshinori Ohsumi

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4.Ichimura,Y.,Kirisako T., Takao, T., Satomi, Y., Shimonishi, Y., Ishihara, N.,Mizushima, N.,Tanida, I., Kominami, E., Ohsumi, M., Noda, T. and Ohsumi, Y.(2000). Aubiquitin-like system mediates protein lipidation. Nature, 408,488-492









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