镁合金可降解层层组装高分子涂层耐蚀性

曾荣昌 山东科技大学

我们通过层层组装在医用镁合金表面制备了一种聚电解质和硅烷复合涂层。该涂层具有较好的耐蚀性并能促进Ca-P盐沉积。    

论文在线发表在FOMS (Corrosion resistance of biodegradable polymeric layer-by-layer coatings on magnesium alloy AZ31, Frontiersof Materials Science, (), 1-13, Doi:10.1007/s11706-016-0332-1)

ABSTRACT:Biocompatible polyelectrolyte multilayers (PEMs) and polysiloxane hybrid coatingswere prepared to improve the corrosion resistance of biodegradable Mg alloy AZ31.The PEMs, which contained alternating poly(sodium 4-styrenesulfonate) (PSS) andpoly(allylamine hydrochloride) (PAH), were first self-assembled on the surfaceof the AZ31 alloy substrate via electrostatic interactions, designated as(PAH/PSS)₅/AZ31. Then, the (PAH/PSS)5/AZ31 samples were dipped into amethyltrimethoxysilane (MTMS) solution to fabricate the PMTMS films, designatedas PMTMS/(PAH/PSS)₅/AZ31. The surface morphologies, microstructures andchemical compositions of the films were investigated by FE-SEM, FTIR, XRD andXPS. Potentiodynamic polarization, electrochemical impedance spectroscopy andhydrogen evolution measurements demonstrated that the PMTMS/(PAH/PSS)5/AZ31composite film significantly enhanced the corrosion resistance of the AZ31alloy in Hank’s balanced salt solution (HBSS). The PAH and PSS films effectivelyimproved the deposition of Ca-P compounds including Ca3(PO4)2 and hydroxyapatite(HA). Moreover, the corrosion mechanism of the composite coating was discussed.These coatings could be an alternative candidate coating for biodegradable Mgalloys.

KEYWORDS:magnesium alloy; polyelectrolyte; polysiloxane; corrosion; layer-by-layer

通过层层组装，我们在AZ31镁合金表面制备了聚电解质/硅烷/庆大霉素复合涂层。该涂层表现出耐蚀和抗菌功能，药物庆大霉素在复合膜层中能释放17天。

论文发表在Surface and Coating Technology (Lijun Liu,Pingping Li, Li Shen, Yuhong Zou, Kaijie Luo, Fen Zhang, Rong-Chang Zeng, Shuoqi Li. Corrosion resistance of superhydrophobicstearic acid modified calcium-phosphate coating on AZ31 alloy. 2016, 291(15):7-14)

Highlights

•A polysiloxane and LbL composite coatingwas prepared on AZ31 alloy.

•The drug release from the composite coatinglasts for 17 days.

•The composite coating shows corrosionresistance and antibacterial effect.

•It is a versatile approach to developfunctional coatings on magnesium implants.

Abstract

An investigation on the corrosion resistance and antibacterial properties ofpolyelectrolytes and polysiloxane coatings on magnesium alloy with gentamicinwas made. The microstructure and composition of the multilayer coatings werecharacterized by using Fourier transform infrared spectroscopy, X-raydiffractometer and scanning electron microscopy. The analysis ofelectrochemical measurement in HBSS suggested that the composite coatingsimproved the corrosion resistance of AZ31 alloy. Finally, the result ofplate-counting method demonstrates the effective antibacterial properties ofthe functionalized substrates. Thus, it can be concluded that themultilayer-treatment reported here is a versatile approach to developantibacterial and anticorrosion coatings on magnesium implants.

Keywords

Magnesium alloy; Corrosion resistance; Antibacterial performance; Polyelectrolyte; Polysiloxane; Gentamicin

利用水热法和层层组织我们还在镁合金AZ31表面制备了氢氧化镁膜、硫酸庆大霉素(GS)和聚苯乙烯磺酸钠(PSS)复合膜层。研究表明，通过水热法和层层组装制备的复合膜层具有较好的耐蚀和抗菌性能。

论文发表在Trans.Nonferrous Met. Soc.（Rongchang ZENG, Lijun LIU, Kaijie LUO, LiSHEN, Fen ZHANG, Shuoqi LI,Yuhong ZOU. In vitro corrosion and antibacterialproperties of layer-by-layer assembled GS/PSScoating on AZ31 magnesium alloys. 25(2015)4028−4039）

Abstract:

To enhance thecorrosion resistance of magnesium (Mg) alloy and to impart its surface withantibacterial functionality for inhibiting biofilm formation and biocorrosion,Mg(OH)2 films have been fabricated on magnesium alloy AZ31 substrates by anin-situ hydrothermal method and well-defined multilayer coatings, consisting ofgentamicin (GS) and poly (sodium 4-styrene sulfonate) (PSS), were prepared vialayer-by-layer (LbL) assembly. The morphologies, chemical compositions andcorrosion resistance of the obtained (PSS/GS)n/Mg composite coating were investigatedusing scanning electron microscopy, Fourier transform infrared spectroscopy,X-ray photoelectron spectroscopy, electrochemical methods and immersion tests.Finally, the bactericidal activity of (PSS/GS)n/Mg samples against Staphylococcusaureus was assessed by the zone of inhibition methods and plate-countingmethod. The so-synthesized multilayer coating on the Mg alloy substratesexhibited good corrosion resistance and antibacterial performance, which make themattractive as coatings for medical implanted devices.

Keywords: Magnesium alloy; Corrosion resistance; Antibacterialproperty; Layer-by-Layer assembly

关键词：镁合金；耐蚀；抗菌性；层层组装

新进展：

Lan-Yue Cui, Rong-Chang Zeng, Shuo-Qi Li et al. Corrosion resistance of layer-by-layer assembled polyvinylpyrrolidone/ polyacrylic acid and amorphous silica films on AZ31 magnesium alloys. RSC Advances, 2016 ,6, 63107-63116.